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Adele ClarksonAdele Clarkson (left panel) is a senior scientist with over 15 years of experience in diagnostic immunohistochemical analytical techniques. She runs a busy diagnostic immunohistochemistry laboratory at Pathology North, Royal North Shore Hospital, a tertiary level healthcare facility which provides diagnostic services for the management of complex malignancies including haematolymphoid and solid organ neoplasms.

 

Adele has expertise in the optimisation of novel antibodies for research and diagnostic immunohistochemistry on formalin fixed paraffin embedded (FFPE) tissue.

 

Angela ChouAngela Chou (right panel) is a fellow of the Royal College of Pathologists of Australasia. She divides her time between a busy clinical practice at SydPath, St Vincent's Hospital, Sydney, and research work at the Garvan Institute of Medical Research where she is a doctoral candidate.

 

Angela's research interest lies in the translational applications of molecular techniques in cancer diagnosis. She is also affiliated with the Australian Pancreatic Cancer Genome Initiative providing specialist input in hepatobiliary and upper gastrointestinal pathology.

 

Kim GeorgeKim George (left) is a senior administrative officer at Pathology North, Royal North Shore Hospital, with extensive experience in medical transcription and pathology data curation and mining.

 

Kim created the foundational datasets for the group and established processes to mine pathology information systems for data which now accompany our tissue resource.

 

Mahtab Farzin (right) is a pathology registrar at Royal North Shore Hospital and a trainee with the Royal College of Pathologists of Australasia. Her research interest lies in the development of potential new cancer diagnostics which can help fine-tune cancer treatment for individual patients.

 

Mahtab has published on the validation of novel biomarkers in pituitary and lung cancers, and is currently involved in the validation of EGFR and ALK mutation specific immunohistochemistry in lung cancer.

 

Michelle HouangMichelle Houang (left) is a pathology registrar at Royal North Shore Hospital, a trainee of the Royal College of Pathologists of Australasia and a 2013 clinical fellow of the Cancer Institute of NSW's Northern Translational Cancer Research Unit.

 

Her 2013 research project investigated the role of embryonic transcription factors in the evolutionary biology of malignant melanoma, with special emphasis on the development of diagnostics which may have clinical relevance in the management of patients with melanoma.

 

The tissue micro-array resource bank (comprised of thousands of paraffin blocks spanning multiple cancer types) are created and curated by Loretta Sioson (right), our research officer.

 

Loretta SiosonShe brings with her a wealth of experience in diagnostic pathology laboratory techniques and is familar with the processing and manipulation of FFPE biospecimens, as well as familiarity with special cytochemical and immunohistochemical techniques.

 

Loretta uses the Veridiam tissue arrayer to create tissue micro-arrays containing 1mm diameter cores. She works with diverse tissue types, including colon, brain, thyroid, breast and lung.

 

Nicole WatsonNicole Watson (left) leverages her extensive computer skills to mine laboratory information systems for clinical and pathological data which are used to annotate FFPE biospecimens.

 

She is responsible for the management and maintenance of our FFPE  BioBank data resource. We currently have over 5000 cases on file encompassing a range of cancer types, projected to increase to over 10,000 cases by the end of the year.

 

Nicole is responsible for the management of the Human Research Ethics Committee (HREC) documentation for the group and advises on new research project ethics submissions.

 

Christopher Toon (right) is a fellow of the Royal College of Pathologists of Australasia and an honourary lecturer at the University of Sydney. He divides his time between research work with the group at the Kolling Institute of Medical Research and diagnostic work at Histopath Pathology.

 

Christopher's interests include the application of biostatistical methods in the elucidation of potential clinical applications of immunohistochemical and molecular based tests, and pathology bioinformatics in particular the use of medical ontologies like SNOMED-CT in pathology information modelling and messaging.

 

Juliana Andrici (left) is a medical graduate and PhD candidate at the University of Sydney. Her research interest is in gastrointestinal cancer, and she has published on the epidemiology and risk factors relating to Barrett's oesophagus, as well as oesophageal and colorectal cancer.

 

For her PhD project, Juliana is currently investigating predictors of malignant progression in Barrett's oesophagus.  She is also collaborating in a number of pathology based projects in a variety of organ systems. Juliana's long term goal is to combine her interest in cancer research with a career in pathology.

 

Shane Battye (right), trained in histopathology at the Austin, Box Hill and Peter MacCallum Cancer Hospitals after graduating from the University of Melbourne. Shane joined TissuPath as a specialist pathologist in 2013 and co-founded the digital pathology hub, Pathobin.

 

His major diagnostic interests include urological and gastrointestinal pathology. Outside of clinical work he has a passion for computer science and has been busy exploring new avenues of digital and virtual pathology.

 

He has prototyped and patented an innovative method of slide digitisation using smartphone, robotics and 3D printed technology and lately has been developing an automated structure from motion photogrammetry system for use in 3D scanning of pathology specimens.

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